array cgh造句
例句與造句
- Microarray comparative genomic hybridization ( array CGH ) shows changes in small amounts DNA on chromosomes.
- With the introduction of array CGH, the main limitation of conventional CGH, a low resolution, is overcome.
- Differentiation between metastatic and mild lesions is also possible using FISH once the abnormalities have been identified by array CGH.
- FISH and array CGH characterization of de novoderivative Y chromosome ( Yq duplication and partial Yp deletion ) in an azoospermic male.
- Advances in genetic testing and more widespread use of Array CGH ( Comparative Genomic Hybridization ) has led to increased diagnosis of MECP2 duplication syndrome.
- It's difficult to find array cgh in a sentence. 用array cgh造句挺難的
- Array CGH may also be applied not only to the discovery of chromosomal abnormalities in cancer, but also to the monitoring of the progression of tumors.
- By array CGH, Slavotinek et al . ( 2005 ) screened patients with DIH and additional phenotypic anomalies consistent with Fryns syndrome for cryptic chromosomal aberrations.
- Targeted 1q21 array CGH investigation of the potential association between DUF1220 and brain size found that DUF1220 copy number decrease is associated with microcephaly in individuals with 1q21 CNVs.
- In array CGH, the metaphase chromosomes are replaced by aberrations in more detail and, moreover, makes it possible to map the changes directly onto the genomic sequence.
- Genes are normally present in two copies in the diploid human genome; genes that deviate from this standard copy number are referred to as array CGH ), or the variant region can be sequenced.
- Array CGH has proven to be a specific, sensitive, fast and highthroughput technique, with considerable advantages compared to other methods used for the analysis of DNA copy number changes making it more amenable to diagnostic applications.
- The gene showing a human-specific increase in DUF1220 copy number was first identified as the result of a genome-wide array CGH study of lineage-specific copy number differences between human and great ape species.
- Through the use of DNA microarrays in conjunction with CGH techniques, the more specific form of array CGH ( aCGH ) has been developed, allowing for a locus-by-locus measure of CNV with increased resolution as low as 100 kilobases.
- The implementation of array CGH, whereby DNA microarrays are used instead of the traditional metaphase chromosome preparation, was pioneered by Solinas-Tolodo et al . in 1997 using tumor cells and Pinkel et al . in 1998 by use of breast cancer cells.
- Array CGH is based on the same principle as conventional CGH . In both techniques, DNA from a reference ( or control ) sample and DNA from a test ( or patient ) sample are differentially labelled with two different fluorophores and used as cDNAs, or oligonucleotides.
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